According to a study reported at the recent Conference on Retroviruses and Opportunistic Infections (CROI 2015) in Seattle, Washington, existing algorithms to screen for anal cancer in women living with HIV could be missing many cases of anal high-grade squamous intraepithelial lesions (HSIL) – abnormal tissue changes that may be a precursor to invasive anal cancer.
Even though the likelihood of a diagnosis of anal HSIL, or high-grade anal dysplasia, by anal tissue examination increased with the degree of abnormality found on anal cytology (anal Pap testing), HSIL diagnoses were made even for women who had less severe abnormalities in their anal Pap tests according to Fanny Ita-Nagy of Mt. Sinai Icahn School of Medicine, who presented the study findings.
You can read the entire article on AIDSMAP
View the webcast from CROI HERE